The developmental characteristics of proactive and reactive aggression in late childhood: The effect of parental control.

Previous research has confirmed that parental control is related to children's aggressive behavior. However, few studies have focused on proactive and reactive aggression to distinguish the different effects of parental psychological and behavioral control. Moreover, additional longitudinal evidence is needed to understand these links. In the current paper, a three-wave longitudinal study was conducted to examine the developmental characteristics of proactive and reactive aggression and the role of parental control in China. A total of 484 4th- and 7th-grade students participated at wave 1 (51.65% in 4th-grade, Mage = 11.66 ± 1.52 years), 465 students (52.04% in 4th-grade) at wave 2, and 447 children (51.90% in 4th-grade) at wave 3. The results showed that: (1) Proactive aggression in late childhood remained stable overall, while reactive aggression displayed a clear upward trend. (2) In proactive aggression, boys and girls had a consistent developmental trend. The initial level of boys was higher than that of girls. In reactive aggression, the growth rate was inversely associated with their initial level and the initial level of boys in 7th-grade was significantly higher than that of girls. (3) Both parental psychological and behavioral control positively predicted students' reactive aggression in 4th- and 7th-grade, whereas only parental behavioral control positively predicted proactive aggression in 7th-grade students, with no gender differences.

Perceived Stress and Mental Health Literacy Among Chinese Preschool Teachers: A Moderated Mediation Model of Anxiety and Career Resilience.

Purpose: Chinese public mental health is currently characterized by a high prevalence of mental ill health and a low consultation rate, due primarily to the nation's low mental health literacy. Previous studies have shown that occupational stress may be a risk factor for mental health literacy. In China, preschool teachers are under high pressure; however, few studies have examined the mechanisms that mediate and moderate the relationship between preschool teachers' feelings of stress and their mental health literacy. Methods: A questionnaire was administered to 2352 preschool teachers to explore the relationship between their stress perceptions and mental health literacy. Results: Preschool teachers' perceived stress was significantly and negatively associated with their mental health literacy, with anxiety playing a partially mediating role. Preschool teachers' career resilience moderated the relationship between perceived stress and anxiety. Perceived stress positively predicted anxiety for teachers with low levels of career resilience; for teachers with high levels of career resilience, perceived stress still positively predicted anxiety, and the higher the level of career resilience, the weaker the positive prediction of stress perception on anxiety. Conclusion: Perceived stress directly predicted mental health literacy among preschool teachers, and also indirectly predicted mental health literacy through the mediating role of anxiety. Career resilience moderated the relationship between stress perception and anxiety. These findings provide new perspectives on the treatment and prevention of preschool teachers' mental ill health.

School bullying and its risk and protective factors in Chinese early adolescents: A latent transition analysis.

Bullying perpetration and victimization are common and problematic occurrences during adolescence. Typically, bullying incidents involve different bullying roles. However, little is known about the developmental stability and changes in these roles. In the present study, we aimed to assess the stability and changes in bullying roles and examine risk and protective factors associated with bullying involvement. A total of 1711 Chinese early adolescents (47.4% girls, Mage = 11.99) participated in the study at two time points approximately 6 months apart. Three subgroups of bullying were identified: bully-victims, victims, and the uninvolved. In terms of stability and changes, the uninvolved were the most stable over time, while victims and bully-victims tended to become the uninvolved. Bully-victims also tended to become victims. Early adolescents with higher levels of parental psychological control and depression symptoms were more likely to be victims or bully-victims. Higher levels of depression symptoms increased the risk of transitioning from being the uninvolved or bully-victims to becoming victims. Higher levels of friendship quality were associated with higher odds of being the uninvolved or transitioning from being victims or bully-victims to becoming the uninvolved. Our findings indicate that bullying roles were relatively stable, with some changes over time. The results also highlight the important function that parental psychological control, friendship quality, and depression symptoms can play in preventing and intervening in bullying.

A short-term follow-up study on the relationship between early adolescent proactive/reactive aggression and sleep quality.

OBJECTIVE/BACKGROUND: Sleep quality is closely related to aggressive behavior. Previous studies rarely focused on the relationship between proactive/reactive aggression and sleep quality through a person-centered approach. METHODS: The Pittsburgh Sleep Quality Index Scale and the Reactive-Proactive Aggression Questionnaire were used to assess 553 elementary and middle school students twice at 6-month intervals to better understand the relationship between proactive/reactive aggression and sleep quality in early adolescence. RESULTS: Findings revealed that (1) Sleep quality was positive longitudinally related to both proactive aggression and reactive aggression; Proactive aggression negatively influenced sleep quality, and reactive aggression did not influence sleep quality longitudinally. (2) The sleep quality of persistent non-aggressors and stopped aggressors was significantly better than that of persistent aggressors and new aggressors. CONCLUSION: In early adolescence, proactive aggression was mutually related to sleep quality. Therefore, future research should focus on the bidirectional association between aggression and sleep quality. In addition, we should improve the sleep quality for different types of aggressors and transformers, especially for new aggressors.

Comparisons of violence exposure within and across contexts in predicting depression among Chinese children and adolescents.

BACKGROUND: Existing research has identified violence exposure as a risk factor for depression among children and adolescents. To date, however, we know little about whether these associations are influenced by the forms (witnessing and victimization) of violence exposure across different contexts (family, school, and community). OBJECTIVE: The present study thus aimed to compare the effects of two forms of violence exposure across and within three contexts. Sex and age differences were also tested in the above associations. PARTICIPANTS AND SETTING: Participants (N = 906, 52.4 % boys, T1: Mage = 11.03) were children and adolescents recruited from elementary and junior schools in Zhejiang Province, China. METHODS: All participants were asked to complete questionnaires about their experiences of various types of violence exposure and depression at two time points with a 12-month interval. SPSS and Mplus were used to analyze the data. RESULTS: Considering the comparison within contexts, witnessing family violence was a more influential predictor than family violence victimization while school violence was the opposite. As for the comparison across contexts, no significant differences were found in the effects of different violence victimization, while the effect of witnessing family violence and community violence were more influential than witnessing school violence. No significant sex differences in the above associations were found. However, community violence victimization was more negatively related to depression among adolescents compared with children. CONCLUSIONS: The associations between violence exposure and depression are influenced by the forms and contexts of violence as well as age groups.

The role of family and peer factors in the development of early adolescent depressive symptoms: A latent class growth analysis.

Few studies have explored the trajectories of Chinese early adolescent depressive symptoms or comprehensively considered the factors of family and peers. The present study aimed to identify the trajectories of depressive symptoms in early adolescence using a school-based sample assessed in three waves. The study also examined whether family and peer factors were significant predictors. A total of 586 Chinese primary and middle school students participated in the survey. A growth mixture model was used to find the trajectories of depressive symptoms, and multinominal logistic regression was used to identify the predictors. Three trajectories were identified, including a stable-low class, an increasing class, and a high-decreasing class. Results indicated that gender, parental psychological aggression and neglect, parental psychological control, traditional bullying/cyberbullying victimization, and friendship quality were significant predictors. However, witnessing intimate partner violence, parental behavior control, and traditional bullying/cyberbullying perpetration could not significantly predict the trajectories. The findings of this study can provide an empirical basis for teachers and clinical interveners to determine different development trajectories of depressive symptoms and carry out prevention and intervention.

Exposure to domestic violence and depressive symptoms in Chinese adolescents: Sleep problems as a mediator.

INTRODUCTION: Exposure to domestic violence has been shown to be an important risk factor of depression in western studies, but has received less attention in Chinese context. Additionally, the underlying mechanism of its link with depression has not been fully studied. With a longitudinal design, we examined the mediating role of sleep problems between exposure to domestic violence and depressive symptoms in Chinese adolescents, and further considered potential age and gender differences in the direct and indirect pathways. METHODS: Participants were recruited from primary and junior high schools in China and were surveyed across two waves with a 6-month interval. There were 1949 participants at Wave 1 and 1283 at Wave 2. Structural equation model was conducted to examine the mediating role of sleep problems in the association between exposure to domestic violence and depressive symptoms. Multigroup analyses were applied to test potential age and gender differences in the process. RESULTS: Participants' exposure to domestic violence predicted increasing sleep problems, which further predicted more depressive symptoms. Age and gender moderated the indirect pathway from exposure to domestic violence to depressive symptoms through sleep problems, such that the mediating effects of sleep problems were significantly stronger in early-age adolescents and girls than middle-age ones and boys. IMPLICATION: Parents should avoid the use of corporal punishment and protect their children from domestic violence. For adolescents who have underwent domestic violence, parents and clinicians might consider to decrease their depressive symptoms by ameliorating sleep problems, especially for the early-age adolescents and girls.

Violence exposure across multiple contexts as predictors of reactive and proactive aggression in Chinese preadolescents.

Based on different functions of aggression, the conceptual distinction of reactive and proactive aggression has been proposed. It is widely acknowledged that adolescents' violence exposure contributes to later perpetration of aggressive behaviors. However, few studies have compared the effects of violence exposure on reactive/proactive aggression based on the forms (i.e., witnessing and being victimized) and the contexts (i.e., family, community, and school), especially in preadolescents. Thus, the relationship between two forms of violence exposure (witnessing and victimization) and later perpetrating reactive and proactive aggression were compared within and across three social contexts in a sample of Chinese preadolescents. Participants were 609 preadolescents 51.9% boys) recruited from five primary schools in China. Information on two forms of violence exposure across multiple contexts and demography were collected at Time 1 (Mage = 10.65), and aggression data (i.e., reactive and proactive aggression) were collected a year later at Time 2. Results evidenced witnessing and being victimized by violence in the home were more consistently related to later perpetration of reactive and proactive aggression. Witnessing family violence was significantly associated with later perpetration of reactive aggression than witnessing violence in the community. Being victimized by violence in the community and the home were significantly associated with later perpetration of proactive aggression than school victimization. These findings provide a deeper understanding of the roles of both types of violence exposure across contexts in later perpetration of aggression during early adolescence.

Development and validation of the Emotional Intelligence Test for Adolescents in a Chinese sample.

Emotional intelligence, or the ability to perceive, understand, and regulate emotions, has been identified as a protective factor for one's adaptation. Measuring emotional intelligence using performance-based approach is thought to be objective and effective. However, performance-based emotional intelligence instruments for non-Western adolescents are rarely available. To facilitate research on emotional intelligence, the present study developed and validated the emotional intelligence test for adolescents (A-EIT) using a Chinese sample. Study 1 (N = 1,536) showed that emotional intelligence consists of three subabilities (i.e., emotion perception, emotion understanding, and emotion regulation) and identified eligible items for each subtest through exploratory factor analysis (EFA). Study 2 (N = 2,568) confirmed the three-factor structure and its measurement invariance across gender and age groups by (multiple-group) confirmatory factor analyses. Both the full test and its three subtests showed acceptable internal consistencies, and their scores increased with age and showed female advantage. Also, the A-EIT scores were significantly correlated with indicators related to emotional and cognitive skills (convergent validity) and were independent of personality (discriminant validity). Additionally, higher scores on the A-EIT were related to better intrapersonal, interpersonal, and academic adaption (criterion validity), as expected. Study 3 (N = 163) provided further convergent validity evidence for each subtest by using validity tools not based on an emotional intelligence framework. Additionally, the A-EIT displayed satisfactory test-retest reliability. Generally, the A-EIT appears to be a valid and reliable instrument to assess adolescents' emotion intelligence, especially those with relatively low level. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

The relationship between phubbing and the depression of primary and secondary school teachers: A moderated mediation model of rumination and job burnout.

BACKGROUND: With the progress of modern technology and the widespread popularization of mobile phones, many new problems related to mobile phones have aroused people's attention. One of the new phenomena is the phubbing. However, previous studies have paid more attention to the influence of phubbing on the phubbees, few researchers have focused on the influence of phubbing on the phubbers and its influencing mechanism. METHODS: In the present study, convenient sampling method was adopted, and 907 (432 males, 47.6%) primary and secondary school teachers were recruited from Shanxi province in China. The teachers were all assessed by a series of self-assessment scales, including Generic Scale of Phubbing, the Maslach Burnout Inventory-General Survey, Ruminative Response Scale, and the Center for Epidemiological Studies Depression Scale. RESULTS: The results showed as follows: (1) After controlling for age and gender, phubbing had a significantly positive link to depression of primary and secondary school teachers. Job burnout partially mediated the relation between phubbing and depression. (3) Moderated mediation analysis further indicated that the relation between job burnout and depression were moderated by rumination. Job burnout was a stronger predictor of depression in low ruminants than in high ones. LIMITATIONS: First, cross-sectional study design was adopted in this study, but it was difficult to infer the causal relationship between variables. Further investigation and verification should be conducted in combination with experiments and follow-up studies, so as to further reveal the mechanism of action between variables. Second, all the data in this study were from the self-report. Although the common method deviation was not obvious, there may be social desirability effect. CONCLUSIONS: These findings imply that phubbing will not only harm the mental health of the phubbees, but also will affect the mental health of the phubbers. The phubbing enhanced the job burnout of primary and secondary school teachers and increased their risk of depression. Compared with high ruminant, job burnout has a stronger predictive effect on depression in low ruminants. Therefore, we should also pay attention to the mental health problems of phubber teachers in primary and secondary schools.

Entrepreneurship Education and Entrepreneurial Intentions of College Students: The Mediating Role of Entrepreneurial Self-Efficacy and the Moderating Role of Entrepreneurial Competition Experience.

This study aims to explore effective ways to improve college students' entrepreneurial self-efficacy and intentions through entrepreneurship education. The survey used a random sample of 804 college students in Zhejiang Province, China. The results show that: (1) In terms of the characteristics of entrepreneurial intention, there are significant differences in gender, entrepreneurial experience, entrepreneurial competition experience, and family background of self-employment. (2) There are significant differences in the characteristics of entrepreneurship education in gender, entrepreneurial competition experience, and the family background of self-employment. (3) In the relationship among entrepreneurship education, entrepreneurial self-efficacy, and entrepreneurial intention, entrepreneurship education is significantly and positively related to entrepreneurial self-efficacy and entrepreneurial intention. Entrepreneurial self-efficacy is significantly and positively associated with entrepreneurial intention. Entrepreneurial self-efficacy plays a complete mediating role between entrepreneurship education and entrepreneurial intention. Entrepreneurial self-efficacy also has a suppressing effect on the relationship between the two. (4) Entrepreneurial competition experience moderates the second half of the mediating effect of entrepreneurial self-efficacy. Finally, the study offers several proposals for the teaching practice of entrepreneurship education.

Upward social comparison on mobile social media and depression: The mediating role of envy and the moderating role of marital quality.

BACKGROUND: The use of mobile social media enables individuals to learn about others' lives, which may lead to upward social comparison. Evidence has shown that upward social comparison on mobile social media can have negative effect for individuals' mental health, such as a higher risk of depression. Previous studies on this issue have mainly focused on adolescents and college students, but less on married adults' well-being. Moreover, mechanisms underlying this association have not been well-documented. METHODS: A total of 514 Chinese married adults (62% female) were recruited from 26 regions in China. They completed measures of upward social comparison on mobile social media, envy, marriage quality and depression. RESULTS: The results showed a positive association between upward social comparison on mobile social media and depression, which was completely mediated by envy. The direct effect of upward social comparison on depression, and the relation between upward social comparison and envy, were both moderated by marital quality. More specifically that upward social comparison on mobile social media was more strongly associated with depression and envy in adults with lower marital quality. LIMITATIONS: This study only focused on the interpersonal factor (i.e., marriage quality) as a moderating variable, not investigating the potential moderating roles of personality factors and other interpersonal factors. In addition, the cross-sectional in design could not examine the causal relationships among the variables. CONCLUSIONS: High marriage quality can protect married adults from the adverse effects of upward social comparison on mobile social media.

Cyberbullying and depression among Chinese college students: A moderated mediation model of social anxiety and neuroticism.

BACKGROUND: Cyberbullying is a serious social issue that can cause a number of psychological and behavioral problems for perpetrators and victims. Previous studies have shown that adolescent victims of cyberbullying are more likely to exhibit depressive symptoms. However, few studies have investigated the relationship between the perpetration of cyberbullying and depression, or the mediating and moderating mechanisms underlying this relationship. METHODS: A questionnaire survey was conducted among 476 college students to investigate the relationships between cyberbullying perpetration and depression, the mediating role of social anxiety, and the moderating role of neuroticism. RESULTS: The results showed that cyberbullying perpetration had a significant and positive predictive effect on depression. Social anxiety partially mediated this relationship. The direct predictive effect of cyberbullying perpetration on depression, and the relation between social anxiety and depression, were both moderated by neuroticism. Cyberbullying perpetration had a greater impact on depression for college students with lower levels of neuroticism and the predictive function of social anxiety on depression was stronger for individuals with low levels of neuroticism too. But neuroticism did not moderate the association between cyberbullying perpetration and social anxiety. LIMITATIONS: This study focused only on the individual variables influencing the relationship between cyberbullying perpetration and depression, and did not examine interpersonal or environmental variables. Also, the cross-sectional research design means that causality cannot be deduced from the results. CONCLUSIONS: Cyberbullying perpetration can predict depression directly, and also indirectly via the mediating role of social anxiety. Neuroticism moderates the relation both between cyberbullying and depression, and between social anxiety and depression. These findings provide new perspectives for the treatment and prevention of depression among college students.

Randomized controlled trial of cognitive behavioural therapy for depressive and anxiety symptoms in Chinese women with breast cancer.

Depressive and anxiety symptoms are frequently observed in breast cancer survivors. To date, few randomized controlled trials have been conducted on the efficacy of cognitive behavioural therapy (CBT) for depressive and anxiety symptoms in Chinese population. This study aims to verify the efficacy of CBT in Chinese breast cancer survivors. Women (n = 392) with breast cancer were randomly assigned to 3 groups: CBT (n = 98), self-care management (SCM, n = 98), and usual care (UC, n = 196) using the proportion 1:1:2. Women in the CBT and SCM groups received a series of nine sessions for 12 weeks, while women in the UC group received their usual medical care only. Depressive and anxiety symptoms were assessed using the Hamilton Depression Rating Scale (HAMD) and the Hamilton Anxiety Scale (HAMA) score at baseline, 2, 4, 8, 12, 16, and 24 weeks. A significant intergroup difference was found in the HAMD and HAMA scores. Women in the CBT group showed significantly less depressive and anxiety symptoms compared with women in the SCM and UC groups over time. In conclusion, this study supports the efficacy of CBT for depressive and anxiety symptoms in Chinese breast cancer survivors.

Effects of cognitive behavioral therapy for depression on improving insomnia and quality of life in Chinese women with breast cancer: results of a randomized, controlled, multicenter trial.

PURPOSE: Cognitive behavioral therapy (CBT) for depression had been found to be effective in reducing depressive and anxiety symptoms in breast cancer survivors. It is not known whether CBT for depression would also improve insomnia and quality of life (QOL). The aim of this study was to investigate whether CBT for depression would improve insomnia and QOL in a randomized controlled multicenter trial. PATIENTS AND METHODS: In this study, breast cancer survivors (n=392) were randomly allocated to the following three groups: CBT (n=98), self-care management (SCM, n=98), and usual care (UC, n=196) in a ratio of 1:1:2. CBT and SCM received a series of nine sessions for 12 weeks, whereas UC received UC only. Insomnia and QOL were evaluated using Athens Insomnia Scale (AIS) and Functional Assessment of Cancer Therapy-Breast (FACT-B) questionnaire at baseline, 4, 12, and 24 weeks. RESULTS: There was a significant intergroup difference in AIS and FACT-B scores (both P<0.01). CBT showed less insomnia problems and better overall QOL compared with those in SCM and UC (both P<0.01). No significant differences were found between SCM and UC in insomnia problems and overall QOL. Moreover, the effects of CBT on insomnia and QOL were maintained during the follow-up period. CONCLUSION: CBT for depression can be effective in improving insomnia problems and QOL in the Chinese breast cancer survivors.

Relationships between Sleep Problems and Psychiatric Comorbidities among China's Wenchuan Earthquake Survivors Remaining in Temporary Housing Camps.

Earthquake survivors are a diverse population. This study focused on a special group of earthquake survivors, who had still stayed in temporary housing camps for about 2 years after China's Wenchuan Earthquake rather than those who moved back to rebuild their lives or immigrated to large cities to seek new lives. The research goals were to (1) assess their sleep problems as well as their PTSD, depression and anxiety and (2) examine the relationship between different dimensions of sleep quality and PTSD, depression, and anxiety among these survivors. Three-hundred and eighty seven earthquake survivors who remained in temporary housing camps and had sleep problems were recruited 17-27 months after Wenchuan Earthquake. Four standardized instruments-The Pittsburgh Sleep Quality Index, PTSD Checklist-Civilian Version, Self-rating Depression Scale, Self-rating Anxiety Scale, and face-to-face one-on-one structured interviews were used to assess these survivors' sleep quality, PTSD, depression, and anxiety. It was found that (1) 83.20% of these survivors reported having sleep problems, and 79.33% of them considered insomnia as the most common sleep problem; (2) 12.14% suffered PTSD, 36.43% experienced depression, and 38.24% had anxiety; (3) sleep disturbance, sleep medication use, and subjective sleep quality were significantly related to PTSD; (4) habitual sleep efficiency, sleep disturbance, sleep medication use, and daytime dysfunction were significantly related to depression; and (5) sleep disturbance, sleep medication use, and daytime dysfunction were significantly related to anxiety. Clinic implications of the study are discussed.

Penetration of erythromycin through Staphylococcus epidermidis biofilm / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>The catheter related infection caused by Staphylococcus epidermidis biofilm is increasing and difficult to treat by antimicrobial chemotherapy. The properties of biofilms that give rise to antibiotic resistance are only partially understood. This study aimed to elucidate the penetration of erythromycin through Staphylococcus epidermidis biofilm.</p><p><b>METHODS</b>The penetration ratio of erythromycin through Staphylococcus epidermidis biofilms of 1457, 1457-msrA, and wild isolate S68 was detected by biofilm penetration model at different time points according to the standard regression curve. The RNA/DNA ratio and the cell density within the biofilms were observed by confocal laser microscope and transmission electromicroscope, respectively.</p><p><b>RESULTS</b>The penetration ratios of erythromycin through the biofilms of 1457, 1457-msrA, and S68 after cultivation for 36 hours were 0.93, 0.55 and 0.4, respectively. The erythromycin penetration ratio through 1457 biofilm (0.58 after 8 hours) was higher than that through the other two (0.499 and 0.31 after 24 hours). Lower growth rate of the cells in biofilm was shown, with reduction of RNA/DNA proportion observed by confocal laser microscope through acridine orange stain. Compared with the control group observed by transmission electrmicroscope, the cell density of biofilm air face was lower than that of agar face, with more cell debris.</p><p><b>CONCLUSIONS</b>Erythromycin could penetrate to the Staphylococcus epidermidis biofilm, but could not kill the cells thoroughly. The lower growth rate of the cells within biofilm could help decreasing the erythromycin susceptibility.</p>

Study on the molecular epidemiological characteristics of norovirus in acute gastroenteritis of Beijing / 中华流行病学杂志

<p><b>OBJECTIVE</b>To study the prevalence, genotypes and molecular characteristics of norovirus (NoV) in acute gastroenteritis.</p><p><b>METHODS</b>RT-PCR was used to determine the molecular epidemiology of NoV.</p><p><b>RESULTS</b>Out of 685 samples, 66 positive specimens were identified and the prevalence was 9.6% (66/685), 9.9% in males and 9.4% in females, respectively, with no significant difference. The prevalence rates showed no differences between age groups or between inpatients and outpatients. NoV gastroenteritis did not present any seasonal distribution. 43 out of the 66 specimens were classified, with 10 (22.7%) belonged to GI including 2 GI.3, 1 GI.4, 4 GI.5 and 3 GI.7. Other 33 (77.3%) belonged to GII genogroup, including GII.4 accounted for 60.6% (20/33) and followed by 7 GII.12, 2 GII.6, 1 GII.2, 1 GII.3, 1 GII.5. Six specimens mixed with GI and GII and 3 specimens were classified as GI.3/GII.7, GI.5/GII.5 and GI.4/GII.4.</p><p><b>CONCLUSION</b>The main symptoms of acute gastroenteritis were abdominal pain, nausea, vomit and fever. There were many genotypes identified in our study and the main genotypes were GII.4/2006a and 2006b. GI and GII could be coinfected with each other.</p>

Viral shedding in Chinese young adults with mild 2009 H1N1 influenza / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>The duration of viral shedding and the transmission of 2009 H1N1 influenza among individuals, especially among the younger population with mild illness, are not well understood now. The aim of this study was to determine the viral shedding of the young adult patients with mild 2009 H1N1 influenza in China.</p><p><b>METHODS</b>From September 2009 to January 2010, the clinical data and serial nasopharyngeal swabs of 67 patients with 2009 H1N1 influenza and 37 patients with seasonal influenza aged from 18 years to 35 years were collected. The nasopharyngeal swab samples were detected by real time RT-PCR to determine the viral shedding. All the patients did not receive the antiviral therapy but Chinese medicine for detoxicating.</p><p><b>RESULTS</b>Among the patients with H1N1 virus infection, 82.1% (55/67) patients presented with fever symptom, while more patients with high fever (≥ 39°C) were found in seasonal influenza patients (P < 0.05). For the H1N1 patients, the median interval between the symptom onset and the undetectable RNA was six days (4 - 10 days). But viral shedding was still found in 31.3% patients after 7 days following illness onset. The median interval between disappearance of fever and an undetectable viral RNA level was three days (2 - 8 days), and 17.9% patients were found to be viral shedding 6 days later after normalization of body temperature. For the seasonal influenza patients, 94.6% patients were detected out viral RNA within 7 days. The median interval of seasonal influenza between the symptom onset and the undetectable RNA was four days (3 - 8 days). The median interval between disappearance of fever and an undetectable viral RNA level was three days (2 - 6 days).</p><p><b>CONCLUSION</b>It suggests that 7 days isolation period from the illness onset or 24 hours after the resolution of fever and respiratory symptoms are not long enough to cut off the transmission among Chinese young adults with mild illness.</p>

Initial knowledge of medical professionalism among Chinese medical students.

BACKGROUND: Initial knowledge of professionalism among medical students is particularly important for designing effective professionalism curricula and for studying the change in the knowledge of professionalism. AIM: The study examined first-semester medical students' initial knowledge of important attributes of good doctors. METHODS: Mixed methods were used to examine initial knowledge among first-semester students from a Chinese medical college. We used an open-ended survey to identify attributes of good doctors and grounded theory analysis to find emergent themes. We also used a close-ended survey to solicit students' responses to 50 attributes of good doctors and explorative and confirmatory factor analysis to examine underlying factors. RESULTS: 973 students completed the open-ended survey while 1730 students completed the close-ended survey. Through grounded theory analysis, 24 subthemes and three themes that include Ethics, Skill, and Person, emerged from the data. Explorative and confirmatory factor analysis showed convergent results: 24 valid items and three factors that include Ethics, Skill, and Person were identified. CONCLUSION: The initial knowledge of medical professionalism among first-semester students involves approximately 24 important attributes within three major dimensions of Ethics, Skill, and Person, with an overwhelming emphasis on Ethics. It is neither sophisticated nor comprehensive, compared with specialists' professional knowledge.